TERT-BUTOXYCARBONYLAMINO-(2-CHLORO-PHENYL)-ACETIC ACID

TERT-BUTOXYCARBONYLAMINO-(2-CHLORO-PHENYL)-ACETIC ACID - Names and Identifiers

Name	[(tert-butoxycarbonyl)amino](2-chlorophenyl)acetic acid
Synonyms	RARECHEM AK ML 0506 N-Boc-(2'-Chlorophenyl)glycine N-BOC-(2'-CHLOROPHENYL)GLYCINE T-BUTOXYCARBONYLAMINO-(2-CHLOROPHENYL)-ACETIC ACID Tert-butoxycarbonylamino-(2-chloro-phenyl)-acetic acid TERT-BUTOXYCARBONYLAMINO(2'-CHLORO-PHENYL)-ACETIC ACID TERT-BUTOXYCARBONYLAMINO-(2-CHLORO-PHENYL)-ACETIC ACID [(tert-Butoxycarbonyl)amino](2-chlorophenyl)acetic acid [(tert-butoxycarbonyl)amino](2-chlorophenyl)acetic acid 2-(TERTBUTOXYCARBONYLAMINO)-2-(2-CHLOROPHENYL)ACETIC ACID 2-Chloro-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]benzeneacetic acid Benzeneacetic acid, 2-chloro-alpha-[[(1,1-dimethylethoxy)carbonyl]amino]- Benzeneacetic acid, 2-chloro-.alpha.-[[(1,1-dimethylethoxy)carbonyl]amino]-
CAS	313490-25-4
InChI	InChI=1/C13H16ClNO4/c1-13(2,3)19-12(18)15-10(11(16)17)8-6-4-5-7-9(8)14/h4-7,10H,1-3H3,(H,15,18)(H,16,17)

TERT-BUTOXYCARBONYLAMINO-(2-CHLORO-PHENYL)-ACETIC ACID - Physico-chemical Properties

Molecular Formula	C13H16ClNO4
Molar Mass	285.72
Density	1.272±0.06 g/cm3(Predicted)
Boling Point	431.5±40.0 °C(Predicted)
Flash Point	214.8°C
Vapor Presure	3.27E-08mmHg at 25°C
pKa	3.26±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.543

TERT-BUTOXYCARBONYLAMINO-(2-CHLORO-PHENYL)-ACETIC ACID - Introduction

[(tert-butoxycarbonyl)amino](2-chlorophenyl)acetic acid is an organic compound with the chemical formula [(tert-butoxycarbonyl)amino](2-chlorophenyl)acetic acid. It has the following characteristics:

Nature:
-Appearance: White crystalline solid
-Molecular weight: 315.75g/mol
-Melting Point: about 110-112 ° C
-Solubility: Soluble in common organic solvents (such as ethers, alcohols, chlorinated hydrocarbons, etc.), insoluble in water

Use:
[(tert-butoxycarbonyl)amino](2-chlorophenyl)acetic acid is a commonly used protecting group in protein chemical synthesis. It can be obtained by reaction with chlorophenylacetic acid, followed by deprotection reaction, or reaction with other molecules to form the target compound.

Method:
[(tert-butoxycarbonyl)amino](2-chlorophenyl)acetic acid can be synthesized by the following steps:
1. First, 2-chlorophenylacetic acid is reacted with N-Boc-glycine anhydride under alkaline conditions.
2. Then, the reaction product was purified by crystallization to obtain [(tert-butoxycarbonyl)amino](2-chroophenyl) acetic acid.

Safety Information:
[(tert-butoxycarbonyl)amino](2-chroophenyl) acetic acid is a general organic compound with low toxicity under normal laboratory operating conditions. However, as a chemical, it can be irritating to the skin, eyes and respiratory system. Therefore, appropriate protective measures should be taken during operation, such as wearing protective glasses, gloves and face masks. If contact occurs, flush the affected area immediately with plenty of water and seek medical help.

Last Update：2024-04-10 22:29:15